Welcome

Our lab is interested in the cellular and molecular mechanisms of brain function. Our research seeks to establish a mechanistic link between pathological neuron function, with an emphasis on voltage-gated ion channels, and behavioral phenotypes.

Our research includes the neuronal pathophysiology in rodent models of neurological disease – including Fragile X syndrome, temporal lobe epilepsy, depression, and tuberosclerosis.

We employ a broad array of approaches including the preparation of acute brain slices, electrophysiological recording including direct dendritic and patch clamp recording, electrical and optogenetic stimulation, and Ca²⁺ imaging. We use biochemical and histological approaches to complement these techniques.